APOE4 Copy Number-Dependent Proteomic Changes in the Cerebrospinal Fluid(1)

BACKGROUND: APOE4 has been hypothesized to increase Alzheimer’s disease risk by increasing neuroinflammation, though the specific neuroinflammatory pathways involved are unclear. OBJECTIVE: Characterize cerebrospinal fluid (CSF) proteomic changes related to APOE4 copy number. METHODS: We analyzed ta...

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Bibliografiska uppgifter
I publikationen:J Alzheimers Dis
Huvudupphovsmän: Berger, Miles, Cooter, Mary, Roesler, Alexander S., Chung, Stacey, Park, John, Modliszewski, Jennifer L., VanDusen, Keith W., Thompson, J. Will, Moseley, Arthur, Devinney, Michael J., Smani, Shayan, Hall, Ashley, Cai, Victor, Browndyke, Jeffrey N., Lutz, Michael W., Corcoran, David L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: IOS Press 2021
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902966/
https://ncbi.nlm.nih.gov/pubmed/33337362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-200747
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