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Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE

Brain iron elevation is implicated in Alzheimer's disease (AD) pathogenesis, but the impact of iron on disease outcomes has not been previously explored in a longitudinal study. Ferritin is the major iron storage protein of the body; by using cerebrospinal fluid (CSF) levels of ferritin as an i...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Ayton, Scott, Faux, Noel G., Bush, Ashley I.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4479012/
https://ncbi.nlm.nih.gov/pubmed/25988319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7760
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