Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line

Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including idiopathic pulmonary fibrosis (IPF). It has been postulated that paracrine mediators originating from senescent alveolar epithelia signal to surrounding mesenchymal cells and con...

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Detalhes bibliográficos
Publicado no:Front Med (Lausanne)
Main Authors: Sullivan, Daniel I., Jiang, Mao, Hinchie, Angela M., Roth, Mark G., Bahudhanapati, Harinath, Nouraie, Mehdi, Liu, Jie, McDyer, John F., Mallampalli, Rama K., Zhang, Yingze, Kass, Daniel J., Finkel, Toren, Alder, Jonathan K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Medicine
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902064/
https://ncbi.nlm.nih.gov/pubmed/33634147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.600626
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