Transcriptional and Proteomic Characterization of Telomere-Induced Senescence in a Human Alveolar Epithelial Cell Line

Cellular senescence due to telomere dysfunction has been hypothesized to play a role in age-associated diseases including idiopathic pulmonary fibrosis (IPF). It has been postulated that paracrine mediators originating from senescent alveolar epithelia signal to surrounding mesenchymal cells and con...

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Udgivet i:Front Med (Lausanne)
Main Authors: Sullivan, Daniel I., Jiang, Mao, Hinchie, Angela M., Roth, Mark G., Bahudhanapati, Harinath, Nouraie, Mehdi, Liu, Jie, McDyer, John F., Mallampalli, Rama K., Zhang, Yingze, Kass, Daniel J., Finkel, Toren, Alder, Jonathan K.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Medicine
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902064/
https://ncbi.nlm.nih.gov/pubmed/33634147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmed.2021.600626
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