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Telomere dysfunction causes alveolar stem cell failure

Telomere syndromes have their most common manifestation in lung disease that is recognized as idiopathic pulmonary fibrosis and emphysema. In both conditions, there is loss of alveolar integrity, but the underlying mechanisms are not known. We tested the capacity of alveolar epithelial and stromal c...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Alder, Jonathan K., Barkauskas, Christina E., Limjunyawong, Nathachit, Stanley, Susan E., Kembou, Frant, Tuder, Rubin M., Hogan, Brigid L. M., Mitzner, Wayne, Armanios, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413294/
https://ncbi.nlm.nih.gov/pubmed/25840590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1504780112
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