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POLR3-Related Leukodystrophy: Exploring Potential Therapeutic Approaches

Leukodystrophies are a class of rare inherited central nervous system (CNS) disorders that affect the white matter of the brain, typically leading to progressive neurodegeneration and early death. Hypomyelinating leukodystrophies are characterized by the abnormal formation of the myelin sheath durin...

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Publicado en:Front Cell Neurosci
Autores principales: Perrier, Stefanie, Michell-Robinson, Mackenzie A., Bernard, Geneviève
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902007/
https://ncbi.nlm.nih.gov/pubmed/33633543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.631802
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