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POLR3-Related Leukodystrophy: Exploring Potential Therapeutic Approaches

Leukodystrophies are a class of rare inherited central nervous system (CNS) disorders that affect the white matter of the brain, typically leading to progressive neurodegeneration and early death. Hypomyelinating leukodystrophies are characterized by the abnormal formation of the myelin sheath durin...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Perrier, Stefanie, Michell-Robinson, Mackenzie A., Bernard, Geneviève
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7902007/
https://ncbi.nlm.nih.gov/pubmed/33633543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.631802
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