Reconsidering anion inhibitors in the general context of drug design studies of modulators of activity of the classical enzyme carbonic anhydrase

Inorganic anions inhibit the metalloenzyme carbonic anhydrase (CA, EC 4.2.1.1) generally by coordinating to the active site metal ion. Cyanate was reported as a non-coordinating CA inhibitor but those erroneous results were subsequently corrected by another group. We review the anion CA inhibitors (...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:J Enzyme Inhib Med Chem
Main Authors: Nocentini, Alessio, Angeli, Andrea, Carta, Fabrizio, Winum, Jean-Yves, Zalubovskis, Raivis, Carradori, Simone, Capasso, Clemente, Donald, William A., Supuran, Claudiu T.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2021
Ábhair:
Review Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901698/
https://ncbi.nlm.nih.gov/pubmed/33615947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2021.1882453
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla