SARS-CoV-2 501Y.V2 variants lack higher infectivity but do have immune escape

The 501Y.V2 variants of SARS-CoV-2 containing multiple mutations in spike are now dominant in South Africa and are rapidly spreading to other countries. Here, experiments with 18 pseudotyped viruses showed that the 501Y.V2 variants do not confer increased infectivity in multiple cell types except fo...

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Vydáno v:Cell
Hlavní autoři: Li, Qianqian, Nie, Jianhui, Wu, Jiajing, Zhang, Li, Ding, Ruxia, Wang, Haixin, Zhang, Yue, Li, Tao, Liu, Shuo, Zhang, Mengyi, Zhao, Chenyan, Liu, Huan, Nie, Lingling, Qin, Haiyang, Wang, Meng, Lu, Qiong, Li, Xiaoyu, Liu, Junkai, Liang, Haoyu, Shi, Yi, Shen, Yuelei, Xie, Liangzhi, Zhang, Linqi, Qu, Xiaowang, Xu, Wenbo, Huang, Weijin, Wang, Youchun
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7901273/
https://ncbi.nlm.nih.gov/pubmed/33735608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2021.02.042
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