501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to bamlanivimab in vitro

The newly emerging variants of SARS-CoV-2 from South Africa (B.1.351/501Y.V2) and Brazil (P.1/501Y.V3) have led to a higher infection rate and reinfection of COVID-19 patients. We found that the mutations K417N, E484K, and N501Y within the receptor-binding domains (RBDs) of the virus could confer ~2...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Liu, Haolin, Wei, Pengcheng, Zhang, Qianqian, Chen, Zhongzhou, Aviszus, Katja, Downing, Walter, Peterson, Shelley, Reynoso, Lyndon, Downey, Gregory P., Frankel, Stephen K., Kappler, John, Marrack, Philippa, Zhang, Gongyi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2021
Assuntos:
Short Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8183533/
https://ncbi.nlm.nih.gov/pubmed/34074219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2021.1919285
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