501Y.V2 and 501Y.V3 variants of SARS-CoV-2 lose binding to Bamlanivimab in vitro

We generated several versions of the receptor binding domain (RBD) of the Spike protein with mutations existing within newly emerging variants from South Africa and Brazil. We found that the mutant RBD with K417N, E484K, and N501Y exchanges has higher binding affinity to the human receptor compared...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:bioRxiv
Principais autores: Liu, Haolin, Wei, Pengcheng, Zhang, Qianqian, Chen, Zhongzhou, Aviszus, Katja, Downing, Walter, Peterson, Shelley, Reynoso, Lyndon, Downey, Gregory P., Frankel, Stephen K., Kappler, John, Marrack, Philippa, Zhang, Gongyi
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory 2021
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899443/
https://ncbi.nlm.nih.gov/pubmed/33619479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/2021.02.16.431305
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registros relacionados