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Copper-Catalyzed Stille Cross-Coupling Reaction and Application in the Synthesis of the Spliceostatin Core Structure

An efficient palladium-free Stille cross-coupling reaction of allylic bromides and functionalized organostannylfUran using catalytic copper halide has been developed. The coupling reaction was optimized using CuI and low catalyst loading (down to 5 mol %). The reaction was conveniently carried out a...

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Veröffentlicht in:J Org Chem
Hauptverfasser: Ghosh, Arun K., Born, Joshua R., Veitschegger, Anne M., Jurica, Melissa S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900942/
https://ncbi.nlm.nih.gov/pubmed/32515594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.0c00976
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