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Enantioselective Synthesis of Spliceostatin E and Evaluation of Biological Activity
[Image: see text] An enantioselective total synthesis of spliceostatin E has been accomplished. The δ-lactone unit A was constructed from readily available (R)-glycidyl alcohol using a ring-closing olefin metathesis as the key reaction. A cross-metathesis of ring A containing δ-lactone and the funct...
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| Publicado en: | Org Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4260646/ https://ncbi.nlm.nih.gov/pubmed/25423085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol503127r |
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