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Synthesis of Aryldifluoroamides by Copper-Catalyzed Cross-Coupling()
A copper-catalyzed coupling of aryl, heteroaryl, and vinyl iodides with α-silyldifluoroamides is reported. The reaction forms α,α-difluoro-α-aryl amides from electron-rich, electron-poor, and sterically hindered aryl iodides in high yield and tolerates a variety of functional groups. The aryldifluor...
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| Publicado no: | Angew Chem Int Ed Engl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4956475/ https://ncbi.nlm.nih.gov/pubmed/26929068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201600105 |
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