Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)

PURPOSE: To examine the contribution of pigment epithelium-derived factor receptor (PEDF-R) to the phagocytosis process. Previously, we identified PEDF-R, the protein encoded by the PNPLA2 gene, as a phospholipase A2 in the retinal pigment epithelium (RPE). During phagocytosis, RPE cells ingest abun...

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Bibliografische gegevens
Gepubliceerd in:Invest Ophthalmol Vis Sci
Hoofdauteurs: Bullock, Jeanee, Polato, Federica, Abu-Asab, Mones, Bernardo-Colón, Alexandra, Aflaki, Elma, Agbaga, Martin-Paul, Becerra, S. Patricia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Association for Research in Vision and Ophthalmology 2021
Onderwerpen:
Biochemistry and Molecular Biology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900850/
https://ncbi.nlm.nih.gov/pubmed/33605986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.62.2.30
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