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PEDF deficiency increases the susceptibility of rd10 mice to retinal degeneration

The SERPINF1 gene encodes pigment epithelium-derived factor (PEDF), a member of the serpin superfamily with neurotrophic and antiangiogenic properties in the retina. We hypothesized that absence of PEDF would lead to increased stress-associated retinal degeneration in Serpinf1 null mice. Accordingly...

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Dades bibliogràfiques
Publicat a:Exp Eye Res
Autors principals: Dixit, Shivani, Polato, Federica, Samardzija, Marijana, Abu-Asab, Mones, Grimm, Christian, Crawford, Susan E., Becerra, S. Patricia
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508969/
https://ncbi.nlm.nih.gov/pubmed/32721425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108121
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