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PEDF deficiency increases the susceptibility of rd10 mice to retinal degeneration
The SERPINF1 gene encodes pigment epithelium-derived factor (PEDF), a member of the serpin superfamily with neurotrophic and antiangiogenic properties in the retina. We hypothesized that absence of PEDF would lead to increased stress-associated retinal degeneration in Serpinf1 null mice. Accordingly...
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| Publicado no: | Exp Eye Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7508969/ https://ncbi.nlm.nih.gov/pubmed/32721425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2020.108121 |
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