A Novel PAK1–Notch1 Axis Regulates Crypt Homeostasis in Intestinal Inflammation

BACKGROUND & AIMS: p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT), and Wingless-related integr...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Frick, Adrian, Khare, Vineeta, Jimenez, Kristine, Dammann, Kyle, Lang, Michaela, Krnjic, Anita, Gmainer, Christina, Baumgartner, Maximilian, Mesteri, Ildiko, Gasche, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900837/
https://ncbi.nlm.nih.gov/pubmed/33189893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2020.11.001
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