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Republished: Tracing PAKs from GI inflammation to cancer
P-21 activated kinases (PAKs) are effectors of Rac1/Cdc42 which coordinate signals from the cell membrane to the nucleus. Activation of PAKs drive important signalling pathways including mitogen activated protein kinase, phospoinositide 3-kinase (PI3K/AKT), NF-κB and Wnt/β-catenin. Intestinal PAK1 e...
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| izdano v: | Postgrad Med J |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BMJ Publishing Group
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4222351/ https://ncbi.nlm.nih.gov/pubmed/25335797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/postgradmedj-2014-306768rep |
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