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Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodrome

An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to intervening in disease course. We developed an animal model—Enhance...

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Publicat a:Sci Rep
Autors principals: Petty, Alice, Cui, Xiaoying, Ali, Asad, Du, Zilong, Srivastav, Sunil, Kesby, James P., Kirik, Deniz, Howes, Oliver, Eyles, Darryl
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900200/
https://ncbi.nlm.nih.gov/pubmed/33619296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83681-4
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