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Positive symptom phenotypes appear progressively in “EDiPS”, a new animal model of the schizophrenia prodrome

An increase in dopamine (DA) synthesis capacity in the dorsal striatum (DS) during the prodromal stage of schizophrenia becomes more pronounced as patients progress to the full disorder. Understanding this progression is critical to intervening in disease course. We developed an animal model—Enhance...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Petty, Alice, Cui, Xiaoying, Ali, Asad, Du, Zilong, Srivastav, Sunil, Kesby, James P., Kirik, Deniz, Howes, Oliver, Eyles, Darryl
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7900200/
https://ncbi.nlm.nih.gov/pubmed/33619296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-83681-4
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