Intratumoral immunotherapy with STING agonist, ADU-S100, induces CD8+ T-cell mediated anti-tumor immunity in an esophageal adenocarcinoma model

Background: Esophageal adenocarcinoma (EAC) is a deadly disease with limited treatment options. STING is a transmembrane protein that activates transcription of interferon genes, resulting in stimulation of APCs and enhanced CD8+ T-cell infiltration. The present study evaluates STING agonists, alone...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Zaidi, Ali H., Kelly, Ronan J., Gorbunova, Anastasia, Omstead, Ashten N., Salvitti, Madison S., Zheng, Ping, Kosovec, Juliann E., Lee, Soyoung, Ayazi, Shahin, Babar, Laila, Finley, Gene G., Goel, Ajay, Jobe, Blair A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2021
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7899550/
https://ncbi.nlm.nih.gov/pubmed/33659041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27886
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