High yield reproducible rat model recapitulating human Barrett’s carcinogenesis

AIM: To efficiently replicate the biology and pathogenesis of human esophageal adenocarcinoma (EAC) using the modified Levrat model of end-to-side esophagojejunostomy. METHODS: End-to-side esophagojejunostomy was performed on rats to induce gastroduodenoesophageal reflux to develop EAC. Animals were...

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Bibliografiske detaljer
Udgivet i:World J Gastroenterol
Main Authors: Matsui, Daisuke, Omstead, Ashten N, Kosovec, Juliann E, Komatsu, Yoshihiro, Lloyd, Emily J, Raphael, Hailey, Kelly, Ronan J, Zaidi, Ali H, Jobe, Blair A
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng Publishing Group Inc 2017
Fag:
Basic Study
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5597499/
https://ncbi.nlm.nih.gov/pubmed/28970723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v23.i33.6077
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