Directed induction of alveolar type I cells derived from pluripotent stem cells via Wnt signaling inhibition

Alveologenesis is a developmental step involving the expansion of the lung surface area which is essential for gas exchange. The gas exchange process is mediated by alveolar type I (AT1) cells, which are known to be differentiated from alveolar type II (AT2) or bipotent cells. Due to the difficulty...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Kanagaki, Shuhei, Ikeo, Satoshi, Suezawa, Takahiro, Yamamoto, Yuki, Seki, Masahide, Hirai, Toyohiro, Hagiwara, Masatoshi, Suzuki, Yutaka, Gotoh, Shimpei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898721/
https://ncbi.nlm.nih.gov/pubmed/33241896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3302
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