A Regulatory Network Involving β‐Catenin, e‐Cadherin, PI3k/Akt, and Slug Balances Self‐Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling

The mechanisms underlying disparate roles of the canonical Wnt signaling pathway in maintaining self‐renewal or inducing differentiation and lineage specification in embryonic stem cells (ESCs) are not clear. In this study, we provide the first demonstration that self‐renewal versus differentiation...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Huang, Tyng‐Shyan, Li, Li, Moalim‐Nour, Lilian, Jia, Deyong, Bai, Jian, Yao, Zemin, Bennett, Steffany A. L., Figeys, Daniel, Wang, Lisheng
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297972/
https://ncbi.nlm.nih.gov/pubmed/25538040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1944
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