A Regulatory Network Involving β‐Catenin, e‐Cadherin, PI3k/Akt, and Slug Balances Self‐Renewal and Differentiation of Human Pluripotent Stem Cells In Response to Wnt Signaling

The mechanisms underlying disparate roles of the canonical Wnt signaling pathway in maintaining self‐renewal or inducing differentiation and lineage specification in embryonic stem cells (ESCs) are not clear. In this study, we provide the first demonstration that self‐renewal versus differentiation...

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Dades bibliogràfiques
Publicat a:Stem Cells
Autors principals: Huang, Tyng‐Shyan, Li, Li, Moalim‐Nour, Lilian, Jia, Deyong, Bai, Jian, Yao, Zemin, Bennett, Steffany A. L., Figeys, Daniel, Wang, Lisheng
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2015
Matèries:
Embryonic Stem Cells/Induced Pluripotent Stem Cells
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5297972/
https://ncbi.nlm.nih.gov/pubmed/25538040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1944
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