In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids

It has been challenging to generate in vitro models of alveolar lung diseases, as the stable culture of alveolar type 2 (AT2) cells has been difficult. Methods of generating and expanding AT2 cells derived from induced pluripotent stem cells (iPSCs) have been established and are expected to be appli...

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Publicado en:Stem Cell Reports
Autores principales: Korogi, Yohei, Gotoh, Shimpei, Ikeo, Satoshi, Yamamoto, Yuki, Sone, Naoyuki, Tamai, Koji, Konishi, Satoshi, Nagasaki, Tadao, Matsumoto, Hisako, Ito, Isao, Chen-Yoshikawa, Toyofumi F., Date, Hiroshi, Hagiwara, Masatoshi, Asaka, Isao, Hotta, Akitsu, Mishima, Michiaki, Hirai, Toyohiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2019
Materias:
Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6409438/
https://ncbi.nlm.nih.gov/pubmed/30773483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.01.014
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