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Functionalization of α‐C(sp(3))−H Bonds in Amides Using Radical Translocating Arylating Groups

α‐C−H arylation of N‐alkylamides using 2‐iodoarylsulfonyl radical translocating arylating (RTA) groups is reported. The method allows the construction of α‐quaternary carbon centers in amides. Various mono‐ and disubstituted RTA‐groups are applied to the arylation of primary, secondary, and tertiary...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Radhoff, Niklas, Studer, Armido
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898318/
https://ncbi.nlm.nih.gov/pubmed/33215815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.202013275
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