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Hypercapnia selectively modulates LPS-induced changes in innate immune and DNA replication-related gene transcription in the macrophage

Hypercapnia, the elevation of CO(2) in blood and tissues, commonly occurs in severe acute and chronic respiratory diseases and is associated with increased risk of death. Recent studies have shown that hypercapnia inhibits expression of select innate immune genes and suppresses host defence against...

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Detalhes bibliográficos
Publicado no:Interface Focus
Main Authors: Casalino-Matsuda, S. Marina, Berdnikovs, Sergejs, Wang, Naizhen, Nair, Aisha, Gates, Khalilah L., Beitel, Greg J., Sporn, Peter H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7898147/
https://ncbi.nlm.nih.gov/pubmed/33633835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsfs.2020.0039
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