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Hypercapnia Suppresses Macrophage Antiviral Activity and Increases Mortality of Influenza A Infection via Akt1

Hypercapnia, elevation of the partial pressure of CO(2) in blood and tissues, is a risk factor for mortality in patients with severe acute and chronic lung diseases. We previously showed that hypercapnia inhibits multiple macrophage and neutrophil antimicrobial functions, and that it increases the m...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Casalino-Matsuda, S. Marina, Chen, Fei, Gonzalez-Gonzalez, Francisco J., Nair, Aisha, Dib, Sandra, Yemelyanov, Alex, Gates, Khalilah L., Budinger, G. R. Scott, Beitel, Greg J., Sporn, Peter H. S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7343622/
https://ncbi.nlm.nih.gov/pubmed/32540997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.2000085
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