Single-cell analysis shows that adipose tissue of persons with both HIV and diabetes is enriched for clonal, cytotoxic, and CMV-specific CD4+ T cells

Persons with HIV are at increased risk for diabetes mellitus compared with individuals without HIV. Adipose tissue is an important regulator of glucose and lipid metabolism, and adipose tissue T cells modulate local inflammatory responses and, by extension, adipocyte function. Persons with HIV and d...

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Gepubliceerd in:Cell Rep Med
Hoofdauteurs: Wanjalla, Celestine N., McDonnell, Wyatt J., Ram, Ramesh, Chopra, Abha, Gangula, Rama, Leary, Shay, Mashayekhi, Mona, Simmons, Joshua D., Warren, Christian M., Bailin, Samuel, Gabriel, Curtis L., Guo, Liang, Furch, Briana D., Lima, Morgan C., Woodward, Beverly O., Hannah, LaToya, Pilkinton, Mark A., Fuller, Daniela T., Kawai, Kenji, Virmani, Renu, Finn, Aloke V., Hasty, Alyssa H., Mallal, Simon A., Kalams, Spyros A., Koethe, John R.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2021
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897802/
https://ncbi.nlm.nih.gov/pubmed/33665640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xcrm.2021.100205
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