Adipose Tissue in Persons With HIV Is Enriched for CD4(+) T Effector Memory and T Effector Memory RA(+) Cells, Which Show Higher CD69 Expression and CD57, CX3CR1, GPR56 Co-expression With Increasing Glucose Intolerance

Chronic T cell activation and accelerated immune senescence are hallmarks of HIV infection, which may contribute to the increased risk of cardiometabolic diseases in people living with HIV (PLWH). T lymphocytes play a central role in modulating adipose tissue inflammation and, by extension, adipocyt...

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Pubblicato in:Front Immunol
Autori principali: Wanjalla, Celestine N., McDonnell, Wyatt J., Barnett, Louise, Simmons, Joshua D., Furch, Briana D., Lima, Morgan C., Woodward, Beverly O., Fan, Run, Fei, Ye, Baker, Paxton G., Ram, Ramesh, Pilkinton, Mark A., Mashayekhi, Mona, Brown, Nancy J., Mallal, Simon A., Kalams, Spyros A., Koethe, John R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6433850/
https://ncbi.nlm.nih.gov/pubmed/30941121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00408
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