Tissue plasminogen activator worsens experimental autoimmune encephalomyelitis by complementary actions on lymphoid and myeloid cell responses

BACKGROUND: Tissue plasminogen activator (tPA) is a serine protease involved in fibrinolysis. It is released by endothelial cells, but also expressed by neurons and glial cells in the central nervous system (CNS). Interestingly, this enzyme also contributes to pathological processes in the CNS such...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neuroinflammation
Päätekijät: Hélie, Pauline, Camacho-Toledano, Celia, Lesec, Léonie, Seillier, Célia, Miralles, Antonio J., Ortega, Maria Cristina, Guérit, Sylvaine, Lebas, Héloïse, Bardou, Isabelle, Vila-del Sol, Virginia, Vivien, Denis, Le Mauff, Brigitte, Clemente, Diego, Docagne, Fabian, Toutirais, Olivier
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2021
Aiheet:
Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897384/
https://ncbi.nlm.nih.gov/pubmed/33610187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02102-5
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