Chemogenetic manipulation of microglia inhibits neuroinflammation and neuropathic pain in mice

Microglia play an important role in the central sensitization and chronic pain. However, a direct connection between microglial function and pain development in vivo remains incompletely understood. To address this issue, we applied chemogenetic approach by using CX(3)CR1(creER/+):R26(LSL-hM4Di/+) t...

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Vydáno v:Brain Behav Immun
Hlavní autoři: Yi, Min-Hee, Liu, Yong U., Liu, Kevin, Chen, Tingjun, Bosco, Dale B., Zheng, Jiaying, Xie, Manling, Zhou, Lijun, Qu, Wenchun, Wu, Long-Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7897256/
https://ncbi.nlm.nih.gov/pubmed/33221486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2020.11.030
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