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Optogenetic activation of spinal microglia triggers chronic pain in mice
Spinal microglia are highly responsive to peripheral nerve injury and are known to be a key player in pain. However, there has not been direct evidence showing that selective microglial activation in vivo is sufficient to induce chronic pain. Here, we used optogenetic approaches in microglia to addr...
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| Publicado en: | PLoS Biol |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8011727/ https://ncbi.nlm.nih.gov/pubmed/33739978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3001154 |
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