Optogenetic activation of spinal microglia triggers chronic pain in mice.
Spinal microglia are highly responsive to peripheral nerve injury and are known to be a key player in pain. However, there has not been direct evidence showing that selective microglial activation in vivo is sufficient to induce chronic pain. Here, we used optogenetic approaches in microglia to addr...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science (PLoS)
2021-03-01
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| Серии: | PLoS Biology |
| Online-ссылка: | https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001154&type=printable |
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