Optogenetic activation of spinal microglia triggers chronic pain in mice.

Spinal microglia are highly responsive to peripheral nerve injury and are known to be a key player in pain. However, there has not been direct evidence showing that selective microglial activation in vivo is sufficient to induce chronic pain. Here, we used optogenetic approaches in microglia to addr...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Min-Hee Yi, Yong U Liu, Anthony D Umpierre, Tingjun Chen, Yanlu Ying, Jiaying Zheng, Aastha Dheer, Dale B Bosco, Hailong Dong, Long-Jun Wu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Public Library of Science (PLoS) 2021-03-01
Цуврал:	PLoS Biology
Онлайн хандалт:	https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.3001154&type=printable
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!