Chemokine-biased robust self-organizing polarization of migrating cells in vivo

To study the mechanisms controlling front-rear polarity in migrating cells, we used zebrafish primordial germ cells (PGCs) as an in vivo model. We find that polarity of bleb-driven migrating cells can be initiated at the cell front, as manifested by actin accumulation at the future leading edge and...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Olguin-Olguin, Adan, Aalto, Anne, Maugis, Benoît, Boquet-Pujadas, Aleix, Hoffmann, Dennis, Ermlich, Laura, Betz, Timo, Gov, Nir S., Reichman-Fried, Michal, Raz, Erez
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2021
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7896345/
https://ncbi.nlm.nih.gov/pubmed/33574063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018480118
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