E-cadherin focuses protrusion formation at the front of migrating cells by impeding actin flow

The migration of many cell types relies on the formation of actomyosin-dependent protrusions called blebs, but the mechanisms responsible for focusing this kind of protrusive activity to the cell front are largely unknown. Here, we employ zebrafish primordial germ cells (PGCs) as a model to study th...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Grimaldi, Cecilia, Schumacher, Isabel, Boquet-Pujadas, Aleix, Tarbashevich, Katsiaryna, Vos, Bart Eduard, Bandemer, Jan, Schick, Jan, Aalto, Anne, Olivo-Marin, Jean-Christophe, Betz, Timo, Raz, Erez
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7588466/
https://ncbi.nlm.nih.gov/pubmed/33106478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-19114-z
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