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Chemokine-biased robust self-organizing polarization of migrating cells in vivo
To study the mechanisms controlling front-rear polarity in migrating cells, we used zebrafish primordial germ cells (PGCs) as an in vivo model. We find that polarity of bleb-driven migrating cells can be initiated at the cell front, as manifested by actin accumulation at the future leading edge and...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7896345/ https://ncbi.nlm.nih.gov/pubmed/33574063 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2018480118 |
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