Loading...
Disentangling selection on genetically correlated polygenic traits via whole-genome genealogies
We present a full-likelihood method to infer polygenic adaptation from DNA sequence variation and GWAS summary statistics to quantify recent transient directional selection acting on a complex trait. Through simulations of polygenic trait architecture evolution and GWASs, we show the method substant...
Na minha lista:
| Udgivet i: | Am J Hum Genet |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier
2021
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7895848/ https://ncbi.nlm.nih.gov/pubmed/33440170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2020.12.005 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|