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Uncovering New Challenges in Targeting Glycolysis to Treat Th17 Cell-Mediated Autoimmunity

Targeting glycolysis in T helper 17 (Th17) cells presents an attractive opportunity to treat Th17 cell-mediated autoimmune diseases such as multiple sclerosis (MS). Pyruvate kinase isoform 2 (PKM2) is a glycolytic enzyme expressed in T cells infiltrating the central nervous system in a mouse model o...

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Bibliografiska uppgifter
I publikationen:Immunometabolism
Huvudupphovsmän: Mosure, Sarah A., Solt, Laura A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2021
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894650/
https://ncbi.nlm.nih.gov/pubmed/33614166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.20900/immunometab20210006
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