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Resolving the Molecular Steps in Clostridial Neurotoxin Light Chain Translocation

The clostridial neurotoxins (CNTs), botulinum toxin and tetanus toxin, are the most toxic proteins for humans. Neurotoxicity is based upon the specificity of the CNTs for neural host receptors and substrates. CNTs are organized into three domains, a Light Chain (LC) that is a metalloprotease and a H...

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Bibliografske podrobnosti
izdano v:J Exp Neurol
Main Authors: Zuverink, Madison, Barbieri, Joseph T.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894615/
https://ncbi.nlm.nih.gov/pubmed/33615314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/Neurol.1.020
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