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Resolving the Molecular Steps in Clostridial Neurotoxin Light Chain Translocation

The clostridial neurotoxins (CNTs), botulinum toxin and tetanus toxin, are the most toxic proteins for humans. Neurotoxicity is based upon the specificity of the CNTs for neural host receptors and substrates. CNTs are organized into three domains, a Light Chain (LC) that is a metalloprotease and a H...

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Bibliografiske detaljer
Udgivet i:J Exp Neurol
Main Authors: Zuverink, Madison, Barbieri, Joseph T.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894615/
https://ncbi.nlm.nih.gov/pubmed/33615314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.33696/Neurol.1.020
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