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Ribociclib enhances infigratinib‐induced cancer cell differentiation and delays resistance in FGFR‐driven hepatocellular carcinoma

BACKGROUND & AIMS: Infigratinib is a pan‐FGFR (fibroblast growth factor receptor) inhibitor that has shown encouraging activity in FGFR‐dependent hepatocellular carcinoma (HCC) models. However, long‐term treatment results in the emergence of resistant colonies. We sought to understand the mechan...

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Podrobná bibliografie
Vydáno v:Liver Int
Hlavní autoři: Prawira, Aldo, Le, Thi Bich Uyen, Vu, Thanh Chung, Huynh, Hung
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894323/
https://ncbi.nlm.nih.gov/pubmed/33179425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14728
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