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Ribociclib enhances infigratinib‐induced cancer cell differentiation and delays resistance in FGFR‐driven hepatocellular carcinoma

BACKGROUND & AIMS: Infigratinib is a pan‐FGFR (fibroblast growth factor receptor) inhibitor that has shown encouraging activity in FGFR‐dependent hepatocellular carcinoma (HCC) models. However, long‐term treatment results in the emergence of resistant colonies. We sought to understand the mechan...

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Bibliografski detalji
Izdano u:Liver Int
Glavni autori: Prawira, Aldo, Le, Thi Bich Uyen, Vu, Thanh Chung, Huynh, Hung
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894323/
https://ncbi.nlm.nih.gov/pubmed/33179425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14728
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