Infigratinib Mediates Vascular Normalization, Impairs Metastasis, and Improves Chemotherapy in Hepatocellular Carcinoma

The fibroblast growth factor (FGF) signaling cascade is a key signaling pathway in hepatocarcinogenesis. We report high FGF receptor (FGFR) expression in 17.7% (11 of 62) of hepatocellular carcinoma (HCC) models. Infigratinib, a pan‐FGFR inhibitor, potently suppresses the growth of high‐FGFR‐express...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Hepatology
Asıl Yazarlar: Huynh, Hung, Lee, Liek Yeow, Goh, Kah Yong, Ong, Richard, Hao, Huai‐Xiang, Huang, Alan, Wang, Youzhen, Graus Porta, Diana, Chow, Pierce, Chung, Alexander
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2019
Konular:
Rapid Communication
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6635738/
https://ncbi.nlm.nih.gov/pubmed/30575985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30481
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller