The actin-regulatory protein Hem-1 is essential for alveolar macrophage development

Hematopoietic protein-1 (Hem-1) is a hematopoietic cell–specific actin-regulatory protein. Loss-of-function (LOF) variants in the NCKAP1L gene encoding Hem-1 have recently been found to result in primary immunodeficiency disease (PID) in humans, characterized by recurring respiratory infections, ast...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Suwankitwat, Nutthakarn, Libby, Stephen, Liggitt, H. Denny, Avalos, Alan, Ruddell, Alanna, Rosch, Jason W., Park, Heon, Iritani, Brian M.
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2021
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7894047/
https://ncbi.nlm.nih.gov/pubmed/33600594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20200472
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