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Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth

Our previous studies found that B16-F10 melanoma growth in the rear footpad of immunocompetent mice induces marked B cell accumulation within tumor-draining popliteal lymph nodes (TDLN). This B cell accumulation drives TDLN remodeling that precedes and promotes metastasis, indicating a tumor-promoti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ganti, Sheila N., Albershardt, Tina C., Iritani, Brian M., Ruddell, Alanna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507466/
https://ncbi.nlm.nih.gov/pubmed/26193241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12255
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