Distinct mechanisms of B and T lymphocyte accumulation generate tumor-draining lymph node hypertrophy

Tumor-draining lymph nodes (TDLNs) often enlarge in human cancer patients and in murine tumor models, due to lymphocyte accumulation and lymphatic sinus growth. B lymphocytes within TDLNs can drive lymph node hypertrophy in response to tumor growth, however little is known about the mechanisms direc...

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Bibliographic Details
Published in:Oncoimmunology
Main Authors: Habenicht, Lauren M., Albershardt, Tina C., Iritani, Brian M., Ruddell, Alanna
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2016
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5007965/
https://ncbi.nlm.nih.gov/pubmed/27622075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1204505
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