Tumor invasion in draining lymph nodes is associated with Treg accumulation in breast cancer patients

Tumor-draining lymph node (TDLN) invasion by metastatic cells in breast cancer correlates with poor prognosis and is associated with local immunosuppression, which can be partly mediated by regulatory T cells (Tregs). Here, we study Tregs from matched tumor-invaded and non-invaded TDLNs, and breast...

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Publicado no:Nat Commun
Main Authors: Núñez, Nicolas Gonzalo, Tosello Boari, Jimena, Ramos, Rodrigo Nalio, Richer, Wilfrid, Cagnard, Nicolas, Anderfuhren, Cyrill Dimitri, Niborski, Leticia Laura, Bigot, Jeremy, Meseure, Didier, De La Rochere, Philippe, Milder, Maud, Viel, Sophie, Loirat, Delphine, Pérol, Louis, Vincent-Salomon, Anne, Sastre-Garau, Xavier, Burkhard, Becher, Sedlik, Christine, Lantz, Olivier, Amigorena, Sebastian, Piaggio, Eliane
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7324591/
https://ncbi.nlm.nih.gov/pubmed/32601304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17046-2
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